📍 Harish Renova Cancer Centre - Alwar- Rajasthan 🕐 Mon–Sat 9AM–6PM
🌞 Head & Neck Cancer

Head & Neck Cancer

A group of cancers that affect the mouth, tongue, throat, voice box, nose, sinuses, and salivary glands. Tobacco and alcohol are the leading causes, while HPV infection is increasingly linked to throat cancers. Early detection can significantly improve outcomes and preserve speech and swallowing functions.

📋 Overview

Head and neck cancer refers to a group of cancers that develop in the tissues and organs of the head and neck region, excluding the brain and eyes. These cancers commonly arise from the squamous cells lining the mouth, throat, and voice box. The most common sites include the oral cavity (mouth), oropharynx (tonsils and base of tongue), larynx (voice box), hypopharynx, nasopharynx, nasal cavity, paranasal sinuses, and salivary glands. Tobacco use, alcohol consumption, and Human Papillomavirus (HPV) infection are major risk factors. At MDCC, Alwar, Dr. Karamvir Yadav offers comprehensive diagnosis, surgery, radiation therapy, chemotherapy, immunotherapy, and rehabilitation services for all stages of head and neck cancers.

🔍 Symptoms to Watch For

  • A mouth ulcer or sore that does not heal within 2–3 weeks
  • Persistent sore throat or throat discomfort
  • Difficulty or pain while swallowing (dysphagia)
  • A lump or swelling in the neck
  • Change or hoarseness of voice lasting more than 3 weeks
  • Red or white patches inside the mouth
  • Loose teeth without dental cause
  • Persistent bad breath (halitosis)
  • Bleeding from the mouth or nose
  • Difficulty opening the mouth fully (trismus)
  • Unexplained weight loss
  • Ear pain without ear infection
  • Blocked nose or persistent nasal congestion on one side

⚠️ Causes & Risk Factors

  • Tobacco smoking, chewing tobacco, gutka, paan, and betel nut use
  • Excessive alcohol consumption
  • Human Papillomavirus (HPV), especially HPV-16 infection
  • Poor oral hygiene and chronic dental irritation
  • Previous head and neck radiation exposure
  • Epstein-Barr Virus (EBV) infection, particularly for nasopharyngeal cancer
  • Occupational exposure to wood dust, asbestos, nickel, and industrial chemicals
  • Weakened immune system
  • Family history of head and neck cancers
  • Poor nutrition and low intake of fruits and vegetables

📊 Types & Stages

Oral Cavity Cancer

Affects lips, tongue, gums, floor of mouth, and inner cheeks. Often linked to tobacco and betel nut use.

Oropharyngeal Cancer

Occurs in the tonsils and base of tongue. HPV-positive cancers generally have better outcomes.

Nasopharyngeal Cancer

Arises behind the nose and above the throat. Often associated with EBV infection.

Salivary Gland Cancer

A rare cancer affecting major or minor salivary glands. Requires specialized treatment.

Stage I–II (Early Stage)

Small localized tumor without lymph node involvement. Usually highly curable with surgery or radiation.

Stage III

Larger tumor or limited spread to nearby lymph nodes. Requires multimodal treatment.

Stage IV

Advanced local disease or distant metastasis involving lungs, bones, or other organs. Requires comprehensive treatment including systemic therapies.

💊 Treatment Options

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Surgery

Primary treatment for many head and neck cancers. May include tumor removal, neck dissection, and reconstructive surgery.

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Immunotherapy

Checkpoint inhibitors such as Pembrolizumab and Nivolumab improve survival in recurrent or metastatic head and neck cancers.

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Targeted Therapy

Cetuximab targets EGFR-positive cancers and may be used alongside radiation or chemotherapy.

Radiation Therapy

Highly effective for early-stage disease and often combined with chemotherapy for advanced cancers.

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Topical Treatments

Imiquimod cream, 5-Fluorouracil, photodynamic therapy for superficial BCC and actinic keratosis.

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Chemotherapy

Used with radiation (chemoradiation) or for recurrent and metastatic disease. Common drugs include Cisplatin, Carboplatin, and 5-FU.

🩺 Diagnosis Methods

  • Comprehensive head and neck examination
  • Flexible nasoendoscopy or laryngoscopy
  • Biopsy of suspicious lesions for histopathological confirmation
  • Fine Needle Aspiration Cytology (FNAC) of neck lymph nodes
  • CT Scan and MRI for local tumor assessment
  • PET-CT scan for staging and detection of distant spread
  • HPV testing for oropharyngeal cancers
  • EBV testing for nasopharyngeal cancers
  • Blood investigations and pre-treatment fitness evaluation

✅ Prevention Tips

  • Avoid all forms of tobacco including smoking, gutka, paan, and chewing tobacco
  • Limit or avoid alcohol consumption
  • Maintain good oral hygiene and regular dental check-ups
  • Receive HPV vaccination when eligible
  • Eat a diet rich in fruits and vegetables
  • Seek medical evaluation for any persistent mouth ulcer or neck swelling lasting more than 2 weeks
  • Use protective equipment when exposed to industrial dust or chemicals
  • Attend regular follow-up examinations if previously treated for head and neck cancer
  • Early diagnosis greatly improves treatment success and helps preserve speech, swallowing, and appearance.
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